16 results
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Clinical Findings ... initial phase of the disease ... Chronic presentation ... of Thiamine deficiency ... Encephalopathy Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Cellular immune deficiency ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Clinical Presentation ... • HLH Labs: ... Treatment: • Corticosteroids ... #Diagnosis #Management
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... , Chronic diarrhoea ... , Short bowel syndrome ... dental fixatives, Treatment ... drkeithsiau #Copper #Deficiency
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... Malnutrition due to chronic ... disease/malabsorptive ... Palpitations • Diarrhea ... hyperparathyroidism Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... Arthritis, AS Treatment ... Recurrent and chronic ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... • Infectious diarrhea ... : • Nephrotic syndrome ... Malignancies • Chronic
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... for and treatment ... ▪ Autoimmune diseases ... Clinical Presentation
Chronic Pancreatitis

Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
fibroinflammatory syndrome ... sensitivity) Clinical ... Fat-soluble vitamin deficiency ... Pancreatitis #diagnosis #management ... gastroenterology #treatment