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diagnosis dermatology signs antimda5 antimda5dm antinxp2 antinxp2dm arteritis autoimmune cutaneous differential disease findings gca giantcell hemeonc hemophagocytic hlh igg4 lymphohistiocytosis
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... - Interstitial lung ... #Diagnosis #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... anti-NXP2 Abs Lung ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... #diagnosis #management ... #rheumatology #
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... biliary, renal, lung ... increased IgG4+ cells ... Disease #diagnosis #management ... workup #treatment #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... them, but urgent rheumatology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Interstitial lung ... Myositis #Myopathy #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... Clinical Presentation ... • Common Signs ... #Hematology #HemeOnc
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