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diagnosis differential algorithm syndrome blood oncology chronic classification cll dermatomyositis leukemia lymphocytic product reactions treatment workup acquired antimda5 antimda5dm antinxp2
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Lung, Bladder, Colon ... • Metabolic disorders ... Myeloproliferative Disorder ... pancytopenia, blast cells ... Algorithm #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Myelodysplastic Disorder ... or λ), Smudge Cells ... Amy Chung, MD, MSc ... #hematology #Markers
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... Lymphoproliferative disorders ... adsorption onto cancer cells ... Syndrome #Diagnosis #Management ... #treatment #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Eosinophilia, 500-1,500 cells ... organ-specific signs ... #Eosinophil #Disorders ... Differential #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... (LP) tumour B cells ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders ... pathophysiology #Hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... • Chronic lung ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Skin: - CLL cells ... or basket cells ... lymphoproliferative disorders ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... lymphocytes, smudge cells ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
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