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diagnosis differential dermatomyositis signs workup dermatology product symptoms treatment vasculitis algorithm anesthesia anesthesiology antimda5 antimda5dm antinxp2 antinxp2dm arteritis autoimmune checklist
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... - Interstitial lung ... Dermatomyositis #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... effusion, Restrictive lung ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... Eosinophilia, 500-1,500 cells ... allergy, drug reaction ... organ-specific signs ... Differential #diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Related Acute Lung ... potassium from lysed cells ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
common immune reaction ... Related Acute Lung ... potassium from lysed cells ... Transfusions #diagnosis #management ... #hematology #reactions
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
female, asian • Systemic ... biliary, renal, lung ... increased IgG4+ cells ... Disease #diagnosis #management ... workup #treatment #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, drug reactions ... purpura: strong sign ... pulses, bruis, or blood ... Large Vessel: Blood ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... ’s CLL Scoring system ... Lymphocytosis: Absolute blood ... workup #oncology #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
sx + signs/sx of ... day, followed by long ... them, but urgent rheumatology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
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