16 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... Myositis #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... rheumatoid arthritis, SLE ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Constrictive Pericarditis on Echocardiogram
A 55-year-old female marathon runner presents to clinic w/ 6-months of worsening breathlessness
She had gained 15 ... ASA, Kussmaul's sign ... edema, and clear lungs ... Echocardiogram #a4c ... #pocus #clinical
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Pediatric Trauma Primary Survey: C-ABCDE
C - Catastrophic Bleeding - Life-threatening hemorrhage
 • Apply direct pressure/compression bandage
Apnea/poor effort, Signs ... Binder) • Use POCUS ... ↓ BP is a late sign ... normalized vital signs ... Survey #CABCDE #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology