25 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
- Heliotrope sign ... or shawl sign ... - Gottron's sign ... - Interstitial lung ... Dermatomyositis #Diagnosis #Rheumatology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Neutrophils - Differential ... Lung, Bladder, Colon ... pancytopenia, blast cells ... #Neutrophils #Differential ... Algorithm #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... adsorption onto cancer cells ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Bulge Sign to demonstrate a Knee Effusion on Physical Examination

Dr. Janet Pope @Janetbirdope

#Bulge #Sign #Knee #Effusion
Bulge Sign to demonstrate ... Janetbirdope #Bulge #Sign ... PhysicalExam #clinical #video ... #orthopedics #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Myositis 4% - Lung ... (aPL) 30-45% Differential ... autoantibodies #signs ... symptoms #mimickers #differential ... #rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... Inflammatory #Myopathies #differential ... diagnosis #comparison #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
biliary, renal, lung ... increased IgG4+ cells ... 40% supporting long-term ... Disease #diagnosis #management ... workup #treatment #rheumatology
The Bulge Sign in Knee Effusion

Highly specific sign for knee joint effusion. 
 - Stroke the
The Bulge Sign in ... Highly specific sign ... TBHMedicine #Bulge #Sign ... Effusion #clinical #video ... orthopedics #sports #rheumatology