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differential management algorithm secondary generalized pruritus rheumatology syndrome activation atopic atopy classification clinical common cutaneous cvid dermatitis dress eczema hemeonc
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
malnutrition) Blue ... discoloration) • Liver ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
- Differential Diagnosis ... • Bullous systemic ... Vesiculobullous #SkinRash ... #dermatology #Differential ... #causes
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... • Transfusion reactions ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... and Primary Causes ... • Cholestatic liver ... renal failure/uremia ... #generalized #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... deficiency • Liver ... fever • Drug reactions ... #hematology #rheumatology ... #nonpalpable #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Edema in 70% of cases ... Criteria for Diagnosis ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
- Differential Diagnosis ... renal failure/uremia ... Pruritus #secondary #systemic ... #generalized #dermatology ... #Algorithm #causes
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Idiosyncratic drug reactions ... Megaloblastic anemia-rare ... #causes #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
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