21 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... pathology and muscle disorders ... disorder and form ... part of the differential ... and a positive Babinski
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness - Differential ... Infection • Neuro: UMN ... stroke, tumor), LMN ... Polyneuropathy, ALS), NMJ disorder ... Generalized #Weakness #Differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... kwburak #LFTs #Elevated ... #Abnormal #Transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... #LiverEnzymes #Differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... injury • Gait is abnormal ... : Areflexia UMN ... plantar response LMN
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
likely - Mid range/ULN ... FeCa <1 %) - Low normal ... • If all normal ... Hypercalcemia #workup #differential ... endocrinology #calcium #elevated
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... Gravis - Lack of UMN ... /LMN signs - Lack ... • Inflammatory disorders
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
IgG typically elevated ... upper limit of normal ... ALT + AST > 10x ULN ... ALT + AST > 5x ULN ... AND IgG > 2x ULN
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
of Anemia with elevated ... Volume (MCV) - Differential ... • Small Bowel Disorder ... Deficiency - Abnormal ... #elevatedMCV #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... specificity to elevated ... - If both are normal ... chemistry #diagnosis #differential