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diagnosis hepatology algorithm transaminitis liver workup atrophy autoimmune biliary calcium chemistry cholangitis cholestatic cirrhosis cord disorders endocrinology enzymes evaluation flaccid
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... form part of the differential ... However, in UMN ... This lesion causes ... and a positive Babinski
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... disease US — Normal ... • Others #LFTs ... Diagnosis #Algorithm #Causes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Burak @kwburak #LFTs ... #Elevated #Abnormal
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... value = (ALT + ULN ... phosphatase + ULN ... Transaminitis #diagnosis #differential
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Evaluation 1) Clinical clues ... likely - Mid range/ULN ... • If all normal ... Hypercalcemia #workup #differential ... endocrinology #calcium #elevated
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... specificity to elevated ... chemistry #diagnosis #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... injury • Gait is abnormal ... Non-compressive Spinal Cord Causes ... : Areflexia UMN ... plantar response LMN
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... or slightly elevated ... early on but elevated ... • ALP > 1.5 x ULN ... bile ducts Differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... kinase levels are elevated ... DM • CPK 10X ULN ... statins - probably caused ... #rheumatology #differential
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