13 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... - CBD stone, Biliary ... Transaminitis #Algorithm ... #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... disease US — Normal ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... Differential #Diagnosis #Algorithm
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
the liver ALP - Biliary ... Phosphatase, ALT ≥ 3x ULN ... Value = (ALT / ULN ... ALT) / (ALP / ULN ... Transaminitis #diagnosis #hepatology
Ascites - Differential Diagnosis and Workup Algorithm

•
Perform paracentesis:
 • Cell count and diff 
 • Total
Diagnosis and Workup Algorithm ... ascites WBC and PMN ... Differential #Diagnosis #Algorithm ... gastroenterology #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... • ALT & AST normal ... No extrahepatic biliary ... • ALP > 1.5 x ULN ... diagnosis #workup #hepatology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
injury • Gait is abnormal ... dysfunction • Abnormal ... : Areflexia UMN ... plantar response LMN ... differential #algorithm
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
upper limit of normal ... ALT + AST > 10x ULN ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... Diagnosis #Management #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... of ALP • Near normal ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Extrahepatic - Biliary ... function may be abnormal ... differential #diagnosis #algorithm ... #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... include extrahepatic biliary ... #Algorithm #Hepatology