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hematology management differential erythematosus leukemia lupus sle systemic workup chronic cll disease hemeonc infections infectiousdiseases lymphocytic ra abnormal acute agglutinin
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... peripheral blood smear ... pylori test (GI symptoms ... changes), high MCV anemia ... #hematology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
Clinical manifestations ... pancreatitis Lungs ... suppression, Anemia ... liver #failure #Signs ... #Symptoms #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... immunophenotype Clinical ... of anemia or thrombocytopenia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
of anemia include ... anemia • Cold ... IgM) • Blood smear ... disease #hemolytic #anemia ... #hematology #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
reticularis Blood: Anemia ... inflammation tends to cause ... interstitial lung ... pathophysiology #signs ... #symptoms #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Peripheral smear ... • Neutropenia, anemia ... #workup #oncology
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