89 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear ... changes), high MCV anemia ... or if a primary hematologic ... dysplasia on the smear ... #Workup #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... Autoimmune hemolytic anemia ... Peripheral #Blood #Smear ... #Analysis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Normochromic RBCs on Smear ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes ... #Hematology
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia ... workup #diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... or negative - Smear ... C3 positive - Smear ... Autoimmune #Hemolytic #Anemia ... Pathophysiology #diagnosis #hematology
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... In this case, the ... Leukoerythroblastosis #Hematology ... #Pathology #Smear
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... Bodies #Pathology #Hematology ... #Smear #Clinical
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... and non-hematologic ... Toxins • Aplastic Anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... C3d • Blood smear ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy