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diagnosis pathophysiology differential neurology autoimmune management myositis acute bulimianervosa complications endocrinology hyperthyroid hyperthyroidism hypothyroid hypothyroidism injury ms multiple myelitis myopathy
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
lumbar spine Signs ... of normal leg reflexes ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... #signs
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... and Signs Hypothyroidism ... ophthalmoplegia) • ± Diffuse ... Dermatopathy Ø Hands ... #Signs #Diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... see mechanics hands
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... clumsiness in hands ... rectal reflex. ... pathophysiology #signs ... #symptoms #msk
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Diffuse Systemic ... esophageal dilation, reflux ... fingers) - Finger/hand ... pathophysiology #signs ... #symptoms #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... occasional oligoclonal bands ... Differential #Diagnosis #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... Oligoclonal IgG bands
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Gottron sign) ... • Shawl sign • ... • Mechanic's hands ... Myositis #Myopathy #rheumatology
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
inflammation -> Acid reflux ... • Boerhaave syndrome ... diffuse glomerulosclerosis ... pathophysiology #diagnosis #signs ... #symptoms #psychiatry
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