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diagnosis oncology rheumatology rash skinrash ulcerative algorithm antinxp2 arteritis blastomycosis causes chronic clinical dermatologic dermatomyositis differentiation distribution erythematosus gap gca
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Hepatomegaly • Skin ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
: • Squamous cell ... cell carcinoma ... fungoides (cutaneous T-cell ... : • Sickle Cell ... ulcerative #skinrash #dermatology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
an old house & works ... heaped up borders); differential ... : basal cell ca, ... squamous cell ca ... Blastomycosis #SkinRash #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... • Induce blast cell ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Most common cytopenia ... blood count with differential ... Syndromes #diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
polyangiitis (GPA) is common ... disease or more commonly ... reticularis Differential ... syndrome • Giant cell ... Polyangiitis #GPA #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #hematology #oncology ... #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
carcinoma • Clear cell ... adenocarcinoma • Non-small-cell ... three days #AntiNXP2DM ... #diagnosis #management ... dermatology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
adherent scale • Basal ... cell carcinoma ... • Squamous cell ... ; pruritis #dermatology ... #rash #differential
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... very remarkable w/differential ... systemic complaints- anemia ... required due to skip
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