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Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework Basophils ... the total white blood ... cell count Basophils ... Is It A Real Basophilia
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... , Thalassemia Basophilic ... #Peripheral #Blood
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... spur cell), Basophilic
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
eosinophils, & basophils ... defined as white blood ... in peripheral blood ... the margins of blood ... NEUTROPHILS #WCC #BASOPHILS
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood ... proerythroblast – basophilic ... #BloodSmear #Blood
Morphologic Findings in Red Blood Cells
Basophilic stippling - Small blue dots in red cells, due to
Findings in Red Blood ... Cells Basophilic ... and grayer than basophilic ... Fragmented red blood ... burr cells) - Red blood
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes: Chronic Blood ... MCV/RBC<13, +/- basophilic
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... eosinophilia, basophilia ... the peripheral blood
Comparison of basophils and mast cells (in bone marrow).

#Basophils #MastCells #Pathology #Marrow #Smear #Microscopy #Comparison #Table
Comparison of basophils ... #Basophils #MastCells
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
nasal mucosa and basophils ... mast cells and basophils ... > Mast cells & basophils