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hematology management anesthesia anesthesiology checklist chronic classification hemeonc leukemia algorithm bradycardia cardiology differential disorders emergencies lymphoma lymphomas lymphoproliferative mds myelodysplasia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can infiltrate ... smear: Smudge cells ... or basket cells ... microglobulin Treatment ... #workup #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... , smudge cells are ... Transformation to large cell ... uw_IMresidency #CLL ... #Leukemia #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... cells. ... Workup: • Full ... Lymphoma Treatment ... classification #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... - 5% RS cells absent ... (LP) tumour B cells ... common - T Cell ... ~10% - B-Cell
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
aggregate foci (>50 cells ... , B cells, and plasma ... cells around salivary ... lymphoma • B cell ... lymphoma • Large B cell
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
remember to tailor treatment ... OR ventilator bellows ... problem (Box C). ❽ Call ... #Checklist #Diagnosis ... #Management #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... OR ventilator bellows ... control (Box C). ❽ Call ... #Checklist #Diagnosis ... #Management #Workup
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... “big & sticky” cells ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... from the plasma cells ... #Diagnosis #Workup
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