9 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... involving the arms ... shows the right arm ... revealed 25% plasma cells ... #Smear #NEJM
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
parasitemia - normocytic RBCs ... multiples per RBC ... Banana-shaped gametocytes are ... peripheral #clinical #microscopy ... #microbiology #
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... 🔬Tumor cells are ... Prolymphocytes #Smear ... Peripheral #Pathology #Microscopy
Plasmodium falciparum trophozoites (and crenated red blood cells) - Blood Smear

A classic presentation of Plasmodium falciparum
crenated red blood cells ... not infected RBCs ... ) are "crenated" ... peripheral #clinical #microscopy ... #malaria #microbiology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
large numbers and are ... Lymphocytosis on CBC ... • Peripheral smear ... : Smudge cells or ... Hypogammaglobulinemia • Warm
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... • Peripheral smear ... lymphocytes, smudge cells ... are characteristic ... Vmphocytosis on routine CBC
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... abnormal under a microscope ... Peripheral blood smear
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
seen on the left arm ... stain (Tzanck smear ... Microscopic examination ... multinucleated giant cells ... #Microscopy #NEJM
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... protein C and S Pathophysiology ... • Peripheral smear ... Schistocytes, helmet cells ... hydration • RBC