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diagnosis hematology management oncology clinical differential pathology signs disease leukemia lysis neurology rheumatology tumor vasculitis workup acanthocytes acutekidneyinjury agglutinin aids
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... SpurCells #McLeod #Syndrome ... #Smear #Pathology ... #Microscopy #Clinical
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... : • Pathophysiology ... Lysis of tumor cells ... #TLS #diagnosis
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... of neoplastic cells ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Peripheral Smear ... abnormal under the microscope ... abnormal under a microscope ... Peripheral blood smear
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... Burkitt, SCLC Cells ... #Tumor #Lysis #Syndrome ... #TLS #Pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
harmful -> Th Cells ... macrophages, mast cells ... or CTLs -> Inflammation ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Clinical Signs/Symptoms ... back pain - Symptoms ... decreased reflexes Pathophysiology ... Detection of AFB by smear ... microscopy Management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... rapid onset of symptoms ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome
Plasmodium falciparum trophozoites (and crenated red blood cells) - Blood Smear A classic presentation of Plasmodium falciparum
crenated red blood cells ... ) - Blood Smear ... in a thin blood smear ... PhD, D(ABMM), MLS ... peripheral #clinical #microscopy
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