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anemia blood differential management agglutinin aiha autoimmune comparison cppd disease fever gout hemolysis infectiousdiseases maha microangiopathic pathology rheumatology transfusion transfusions
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... - Warm vs Cold ... or negative - Smear ... : spherocytes Cold ... #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... polychromatophilic cells ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... IgM) • Blood smear ... sensitize red blood cells ... passage of red-brown urine ... #anemia #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Autoimmune: Warm AIHA, Cold ... AIHA, Transfusion reactions ... Peripheral Blood Smear ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... flank pain, dark urine ... potassium from lysed cells ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
flank pain, dark urine ... Blood products contain ... potassium from lysed cells ... #Transfusion #diagnosis ... #management #hematology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... Pyrophosphate produced ... A reaction to phagocytosed ... Gout #Comparison #rheumatology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... polymerase-chain-reaction ... chest film; blood-smear ... examination; and urine ... dipstick test, microscopic
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