48 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... 🔬Tumor cells are ... 𝐩𝐫𝐨𝐥𝐲𝐦𝐩𝐡𝐨𝐜𝐲𝐭𝐞𝐬: small to medium ... size lymphoid cells ... Prolymphocytes #Smear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... anemia Sickled red cells ... disease Bite cells ... Alcohol abuse, Heavy metal ... Peripheral #Blood #Smear
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... neutrophil count < 500 cells ... Progressive decline in mental ... Constipation • Nausea ... Hyponatremia • Nausea
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Chronic Otitis Media ... Inferior through medial ... under SCM • Medially ... hearing loss, nausea ... symptoms #diagnosis #otology
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Peripheral blood smear ... History • Bite cells ... Deficiency • Sickle cells ... Diagnosis #Algorithm #causes
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
In this case, arrows ... point to helmet cells ... cell, 2 blister cells ... acanthocyte), and 2 burr cells ... BloodSmear #Blood #Smear
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Reed-Sternberg Cells ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Peripheral Smear ... Exposure to heavy metal ... Peripheral blood smear ... diagnosis #hematology #oncology