10 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... inhibition (NSAIDs, Beta-Blockers ... differential #diagnosis #pathophysiology ... #pharmacology #potassium ... #medications #druginduced
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Beta-Blockers in ... Cirrhosis • Pathophysiology ... • Indications: ... , Carvedilol #BetaBlockers ... #pharmacology #indications
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Antiarrhythmic Medications ... Vaughan Williams Classification ... this class are beta ... III agents - Potassium ... #Classification
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Release: NSAIDs, Beta-Blockers ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... Pharmacology #Impaired #Potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... adrenergic receptor blockers ... Medications 2.
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... • Beta blockers ... cell membrane - Beta ... adrenergic receptor blockers ... Medications 2.
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... duration CLASS 2 - Beta ... repolarization CLASS 3 - Potassium ... alpha & beta adrenergic ... #Classes #pathophysiology
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
Causes of Hyperkalemia ... hyperosmolality - Medications ... : beta blockers, ... tacrolimus - Hyperkalemic ... Diagnosis #Causes #potassium
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... duration CLASS 2 - Beta ... repolarization CLASS 3 - Potassium ... alpha & beta adrenergic ... #Classes #pathophysiology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Beta-Adrenergic ... angiotensin receptor blockers ... inhibitors, ß-blockers ... Diagnosis #High #Potassium ... #Classification