1417 results
Differential Diagnosis of Biliary Duct Dilation #Diagnosis #EM #IM #GI #Biliary #Bile #Duct #Dilatation #Differential #Algorithm
Differential Diagnosis ... of Biliary Duct ... Dilation #Diagnosis ... #Bile #Duct #Dilatation ... #Differential #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Algorithm Severe ... Duct Stone • Biliary ... #Differential #Diagnosis ... #Algorithm #Causes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Algorithm for Transaminitis ... • US - Normal Bile ... • US - Dilated Bile ... - CBD stone, Biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... PSC - Other biliary ... diseases/Bile duct ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Extrahepatic - Biliary ... #differential #diagnosis ... #algorithm #hepatology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action of Bile ... Sequestrants Bile ... Sequestrants → ↓ Hepatic Bile ... Pool → ↑ Hepatic Bile ... Plasma LDL-C #biliary
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
the liver ALP - Biliary ... tree or bile flow ... abnormality vs bone Bili ... Transaminitis #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... antibodies PBC Diagnosis ... No extrahepatic biliary ... Differential Diagnosis ... #cholangitis #diagnosis
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
genes coding for bile ... Dysfunction - Biliary ... certain drugs, biliary ... external pressure on bile ... Classification #diagnosis
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... gradual loss of bile ... inflammation and biliary ... #PBC #Primary #Biliary