66 results
diagnosis differential dermatology hepatology rheumatology causes management algorithm skin clinical liver injury photo vasculitis acute ascites autoimmune classification disease oncology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
predominantly indirect bilirubin ... • Increased bilirubin ... ) • Impaired bilirubin ... Faulty excretion of bilirubin ... hepatocyte damage (eg, hepatitis
DRESS Syndrome vs SJS/TEN DRESS • Latency: 2-8 weeks • Rash: Morbilliform • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... leukocytosis • Hepatitis ... : 4-28 days • Rash ... Lymphopenia • Hepatitis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... autosomal recessive syndrome ... Crigler-Najjar Syndromes ... #hepatology #diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... disease: > 2 • NASH ... • Gilbert's syndrome ... #differential #Hepatology
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
Sweet’s Syndrome ... fever, painful rash ... #Sweets #Syndrome ... neutrophilic #dermatosis #dermatology ... #Rash #Skin #Clinical
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
vein: Budd-chiari syndrome ... disease: > 2 • NASH ... Chronic viral hepatitis ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
normal - Ischemic Hepatitis ... - Acute Viral Hepatitis ... , Toxic Hepatitis ... normal - Hemolysis, NASH ... Liver #Injury #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
fold elevation, Bilirubin ... necrosis HELLP Syndrome ... fold elevation, Bilirubin ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
• Budd-Chiari Syndrome ... Infectious • Hepatitis ... • Alcoholic Hepatitis ... • Drug Induced Hepatitis ... Algorithm #Causes #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Vascular: Budd-chiari syndrome ... Sinusoidal obstruction syndrome ... • Autoimmune hepatitis ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
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