5 results
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of Malignancy ... - Pathophysiology ... intestinal calcium absorption ... in the bone • ... Differential #Diagnosis #algorithm
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
be used by the bone ... cause increased GI absorption ... of iron. ... Malignancy - 24% ... Hematologic Malignancy
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Differential Diagnosis Algorithm ... /lsotretinoin Malignancy ... Cytokine-Mediated Bone ... Resorption (e.g ... Lymphomas) Metastatic Bone
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
Bone resorption ... that facilitate resorption ... an increase in ion ... #Pathophysiology ... #Resorption #RANKL
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
incr gut Ca2+ absorption ... is inhibited by iron ... phosphorous in bones ... Signs #Symptoms #Pathophysiology