6 results
diagnosis differential signs symptoms chondrocalcinosis complications cppd disease disruptors endocrinology fracture healing hypercalcemia hyperferritinemia msk orthopedics osteoclasts pagetsdisease pseudogout rankl
Bone resorption and the relationship between osteoblasts and osteoclasts. RANK is expressed on the osteoclasts,
Bone resorption ... an increase in ion ... #Pathophysiology ... #Osteoclasts #Bone ... #Resorption #RANKL
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of Malignancy ... - Pathophysiology ... intestinal calcium absorption ... in the bone • ... Differential #Diagnosis #algorithm
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
be used by the bone ... increased GI absorption ... of iron. ... Malignancy - 24% ... Hematologic Malignancy
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
forms bony callus ... Fluoroquinolones - Causes ... Insufficient Ca2+ & PO4- absorption ... from GI tract, bone ... #msk #Staging #pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Complications Abnormal Osteoclasts ... cause excessive ... > Incr bone resorption ... resorption, Incr ... PagetsDisease #pathophysiology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... incr gut Ca2+ absorption ... is inhibited by iron ... phosphorous in bones ... Signs #Symptoms #Pathophysiology
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