2838 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
of clinical and biological ... evidences, Biological ... confusion • Biological ... immunosuppressants or biologics ... Drugs, Unknown cause
Delayed Fracture Healing - Non-Union - Malunion - Differential Diagnosis Algorithm

Inflammation (Hours-Days) -> Soft Callus (Days-Weeks)
Allergies • Biologic ... #Orthopedics #Causes
Subglottic stenoses (SGS) during systemic diseases
Subglottic stenosis (SGS) = congenital (children) or acquired (adult) characterized by
Diagnostic Work-up: • Biology ... PET-CT Acquired causes ... differential #diagnosis #causes
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... Other biologics
Drugs Causing Acute Pancreatitis

Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
Biologic Events Leading to Chronic GVHD #Pathophys #Honc #Pharm #GVHD #GraftVersusHostDisease #Therapeutic #Pathways #NEJM
Biologic Events
Algorithm for the Evaluation of Diplopia: Diplopia has been explored previously on ddxof. The earlier algorithm
This algorithm uses ... identify potential etiologic ... causes of diplopia
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Nodosum #Mnemonic #Causes
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
Biologic therapy ... eosinophilic #asthma #Biologic
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Immunomodulatory/Biologic