10 results
Milk of Urate Bulla - A new blister overlying the radial aspect of the second interphalangeal
of negatively birefringent ... Bulla #Negatively #Birefringent
Arthrocentesis - Joint Fluid Analysis

Effusion Characteristics (Color, Clarity, WCC, PMN, Crystals, Bacteria) by Disease Process: 
OA,
Pseudogout (positively birefringent ... Gout (negatively birefringent
Monoarthritis - Differential Diagnosis
Infection (Acute):
 - S. aureus (most common)
 - S. pneumonia
 - Salmonella (in
early in dz, neg birefringent ... /l wrists, pos birefringent
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Needle-shaped, negative birefringent
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
Weakly positively birefringent ... or not birefringent ... Needle-shaped, negatively birefringent
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
Crystals - Positively birefringent
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
an apple-green birefringence
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Weakly positively birefringent ... or not birefringent
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
red: apple-green birefringence
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Needle-shaped, negatively birefringent