1782 results
Arthrocentesis - Joint Fluid Analysis

Effusion Characteristics (Color, Clarity, WCC, PMN, Crystals, Bacteria) by Disease Process: 
OA,
, Bacteria) by Disease ... Pseudogout (positively birefringent ... Gout (negatively birefringent
Monoarthritis - Differential Diagnosis
Infection (Acute):
 - S. aureus (most common)
 - S. pneumonia
 - Salmonella (in
species - Lyme disease ... early in dz, neg birefringent ... /l wrists, pos birefringent
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Weakly positively birefringent ... or not birefringent ... Needle-shaped, negatively birefringent
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
Crystals - Positively birefringent ... Pseudogout #CPPD #Disease
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... • Underlying disease ... Weakly positively birefringent ... or not birefringent ... monoarticular CPPD disease
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
the extent of disease ... red: apple-green birefringence
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... glomerulonephritis - Berger disease ... Minimal change disease ... #Glomerular #Diseases
General overview of lung diseases. 

#diagnosis #causes #lung #disease #restrictive #obstructive #pulmonary #respiratory #pearls #ddxof
overview of lung diseases ... #causes #lung #disease
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Needle-shaped, negative birefringent
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
reaction - Atopic disease ... lymphomas, Hodgkin disease ... Chronic inflammatory diseases ... , IgG4-related disease ... inflammatory bowel diseases