115 results
Blast Injury Categories
 - Primary - Direct effect from blast shockwave 
 - Secondary - Impact
Blast Injury Categories ... Direct effect from blast ... - Tertiary - Blast ... Trauma #Diagnosis #Blast
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
leukemias > 20% blasts ... leukemia < 20% blasts ... lymphadenopathy • Blast ... Rapidly rising blast ... crises • Blasts
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
(pancytopenia, blast
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Leukemia with blast
Binaural Tympanic-Membrane Perforations after Blast Injury #Clinical #ENT #TM #TympanicMembrane #Perforation #BlastInjury #NEJM
Perforations after Blast
Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
aspiration revealed 5% blasts
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
Christ my nerves, Blast
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cytokine Release from blast ... damage • Induce blast
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
cells are NOT blasts
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
feature of these blasts