9 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Fibrillation, VTE ... patients 5mg bid Dabigatran ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Rivaroxaban #Dabigatran
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
- HAS-BLED (atrial ... ) and IMPROVE (VTE ... validated for VTE ... of withholding anticoagulation ... #Factors #Hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... first variceal bleeding ... gastropathy • Dosing ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
clearance (calculated using ... and procedural bleeding ... with a very low bleeding ... of Therapy • Dabigatran ... Management #Treatment #pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... risk during follow-up ... risk of recurrent VTE ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... lead to severe bleeding ... management #algorithm #pharmacology ... decisionaid #cardiology #hematology ... #warfarin #dosing
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... Anticoagulation ... the mainstay of VTE ... #Pharmacology #Pathophysiology ... LMWH #UFH #DOAC #Dabigatran
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
During the initiation ... diagnosis #models #hematology ... #pathophysiology ... #anticoagulation ... anticoagulant #Warfarin #Dabigatran