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management differential lupus neurology arthritis druginduced erythematosus joint pain physicalexam summary systemic workup algorithm approach cardiology cerebritis clinical cns comparison
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... permeability Diagnosis ... Erythematosus #SLE ... CNS #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... arthritis - SLE ... #msk #physicalexam
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia Crises ... Myasthenia #Gravis #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... weeks) Can Be Caused ... arthritis • SLE ... #Differential #Diagnosis ... #MSK #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... We may ask why are ... Ask some questions ... some time, let’s see ... about secondary causes
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE ... Transverse Myelitis Treatment
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... Like in this case ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
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