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diagnosis treatment differential syndrome lupus sle erythematosus cardiology hematology infectiousdiseases signs summary symptoms workup activetb adultonset algorithm aosd autoantibodies comparison
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... solid cancers • Systemic ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Systemic histoplasmosis ... Differential #Diagnosis #Hematology
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
Rheumatic Disease ... Sclerosis, Sjogren's Disease ... , Sarcoidosis, Still's ... Disease, Inflammatory ... Differential #Diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... SSc: systemic sclerosis ... arthritis SLE : systemic ... Comparison #Table #Pulmonary ... #Rheumatology #
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... : Diffuse skin disease ... , Pulmonary fibrosis ... (~93-95%), Pulmonary ... Autoantibodies #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... episode (30%) Systemic ... #rheumatology #diagnosis ... #management #treatment
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... calcinosis • Pulmonary ... interstitial lung disease ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• Homogeneous: Systemic ... ) • Speckled: Systemic ... • Peripheral: Systemic ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... • MCTD (SLE/systemic ... @AnnKumfer #Systemic ... Summary #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... • Adult-onset Still ... disease • Systemic ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
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