388 results
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
B12 and Folate Deficiency ... • B12 Deficiency ... elevated • Folate Deficiency ... Thomas DeLoughery @Bloodman ... #MMA #folate #deficiency
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... Thomas DeLoughery @Bloodman ... TTPHUS #HELLP #AFLP
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... 1948 by Rathbun ALP ... hypothyroidism • Zinc deficiency ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Iron Deficiency ... TIBC-specific for iron deficiency ... Tom DeLoughery @Bloodman ... #Iron #Deficiency
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Pregnancy - AFLP ... • AIH • A1AT deficiency
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Tom DeLoughery @Bloodman ... TTPHUS #HELLP #AFLP
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate Deficiency ... develop folate deficiency ... functional folate deficiency ... Thomas DeLoughery @Bloodman ... #Folate #deficiency
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
Nephritis • AFLP
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... to diagnosis deficiency ... levels will be deficient ... accumulate in B12 deficiency ... tests for B12 deficiency