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diagnosis differential algorithm management hematology hepatology clinical nephrology workup anemia treatment pathophysiology pulmonary rheumatology syndrome urine classification hematuria neurology oncology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... • LDH: Heart, RBC
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... - Increased ALP ... Intestine - Other causes ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... child * Severe cases ... Thomas DeLoughery @Bloodman ... TTPHUS #HELLP #AFLP
Causes of AKI in Pregnancy - Differential Diagnosis Creatinine - Platelets - Transaminases - LDH - PT/PTT
Causes of AKI in ... Nephritis • AFLP ... Differential #Diagnosis #Causes
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... obstruction • ALP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... Bile Ducts • PSC ... Diagnosis #Algorithm #Causes
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
child * Severe cases ... Tom DeLoughery @Bloodman ... TTPHUS #HELLP #AFLP
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct of 70-80% - RBC ... X 1010); some WBC ... plasma, a few RBC ... Tom DeLoughery @Bloodman
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
(Alk phos/ULN ALP ... • AST/ALT > ALP ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC
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