9 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... instability - New-onset ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... characterized by sudden onset ... Monosodium urate deposition ... • Nocturnal onset ... Gout #Comparison #rheumatology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... joint (sudden onset ... #Disease #Signs ... #Symptoms #Pathophysiology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition ... Pathophysiology ... characterized by sudden onset ... Pyrophosphate #Deposition ... #Disease #Rheumatology
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Pyrophosphate Dihydrate (CPPD ... ) Deposition Disease ... - Acute CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... intracellular contents ... diagnosis #management #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... clinical symptoms/signs ... elevation and clinical context ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Monosodium urate deposition ... • Nocturnal onset ... double contour sign ... +Radiographic signs ... management #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
- Onset: Usually ... Presentation • Common Signs ... Pathophysiology ... Diagnosis #Management #Hematology