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diagnosis differential folicacid hematology management pathophysiology ascorbicacid blood dm2 elevation false hba1c hgba1c hyperkalemia increase laboratory product reactions reduction refeeding
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Iron, B-12, or folate ... deficiency • ... Content • RBC Transfusions ... blood loss • Hemolytic
Folate Deficiency - Causes of Decreased Folic Acid ↓ Intake: Diet, Age, Alcohol ↑ Demand: Pregnancy, Infancy, Hemolysis,
Folate Deficiency ... - Causes of Decreased ... Pregnancy, Infancy, Hemolysis ... @drkeithsiau #Folate ... differential #diagnosis #nutrition
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... pregnant have hemolytic ... that can cause ... anticonvulsants lead to increase ... diagnosis #hematology #nutrition
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... recipients w/ IgA deficiency ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
initiation of nutrition ... Hypo-Mg2+ • Vitamin deficiency ... (thiamine) Late ... • Seizures • Hemolysis ... • Vitamin D deficiency
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... persons with poor nutrition ... lead to iron and folate ... contribute to nonimmune hemolysis ... , or any other cause
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... Tourniquet use - Hemolysis ... Potassium-containing drugs - Transfusion ... aged blood - Hemolysis ... tissue necrosis Decreased
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