156 results
Pancytopenia - Differential Algorithm / Schema

- Bone Marrow Failure
- Bone Marrow Infiltration
- Sequestration / Destruction

#Pancytopenia #Differential
/ Schema - Bone ... Marrow Failure - Bone ... Algorithm #Schema #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
production: • Bone ... suppression • Bone ... marrow failure • Bone ... Diagnosis #Algorithm #hematology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
hyperCalcemia 28% (bone ... • Anemia 78% (bone ... macrocytic • Bone ... Diagnosis - Clonal bone ... clonal cell in bone
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... Hematogenous spread as source ... BrighamChiefs #Bone ... diagnosis #causes #hematology
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... by an ↑ rate of bone ... and formation of bone ... mosaic" lamellar bone ... #diagnosis #management
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Renal disease - Bone ... DDX of Hepatic source ... Diagnosis #Algorithm #hepatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... as the collar bone ... #diagnosis #management
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
algorithm for bone ... significance (MGUS) A bone ... algorithm #diagnosis #management ... #hematology #multiplemyeloma
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Hallucinations, Fatigue • Hematologic ... Heart failure • Bones ... Growth retardation, Bone
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia and Bone ... anemia #diagnosis #Hematology