32 results
diagnosis hematology management signs differential leukemia mgus monoclonal summary syndrome treatment workup arthritis chronic cll complications gammopathy hemophagocytic hlh hodgkins
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... : B symptoms, lymphadenopathy ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology ... #differential #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... more: • Clonal bone ... chain deposition disease ... MGUS #diagnosis #hematology ... #oncology
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... Pathophsiology ... Osteonecrosis, bone ... #Gauchers #Disease ... Diagnosis #Signs #Symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... extramedullary disease ... #Leukemia #Hematology ... #Oncology #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... Clinical Signs/Symptoms ... decreased reflexes Pathophysiology ... of bacilli to bone ... CMC_IM #Potts #Disease
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Splenomegaly 5) Symptoms ... chemotherapy for low-risk disease ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... • Autoimmune diseases ... Adult-onset Still disease ... treatment #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
• Ligament • Bone ... or nerve root Symptoms ... of Joint Disease ... categories of joint disease ... Joint #Pain #MSK #rheumatology
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