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diagnosis nephrology urine clinical differential causes granular acute hematuria muddybrown abscess ain aki amebic atlas atn blood bloodsmear borrelia clinicopathology
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy Brown ... ” Casts on Urine ... Microscopy A. ... (c) and muddy brown ... #Urine #Microscopy
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Muddy Brown Granular ... Casts three ways ... vipvargh #Muddy #Brown ... #Granular #Casts ... clinical #urine #microscopy
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... Casts • Hyaline ... • "Muddy Brown ... #Urine #Microscopy
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
granular/waxy mixed casts ... granular/muddy brown ... C and D: muddy brown ... Granular #MuddyBrown #Casts ... #Urine #Microscopy
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... fresh at time of microscopy ... • Red cell casts ... disease • “Muddy brown ... contamination #Urine #Microscopy
Muddy Brown Casts in ATN #Clinical #Path #Nephro #Urine #Microscopy #MuddyBrownCasts #ATN
Muddy Brown Casts ... Nephro #Urine #Microscopy
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... "Muddy-brown" heme-granular ... casts are seen ... #Differential #Microscopy
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts ... Nephritis #AIN #Algorithm
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain + gross or microscopic ... hematuria: - RBC casts ... Dysmorphic RBC - Brown
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... cells on urine microscopy ... RBCs and/or RBC casts ... with polyangiitis/microscopic ... Differential #Diagnosis #Algorithm
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