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diagnosis rheumatology classification differential management vasculitis comparison druginduced types allergy biopsy clinicopathology cryoglobulinemia cryoglobulins dil erythematosus gi glomerulonephritis hypersensitivity ileitis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... 80% - Low complement ... #lupus #Systemic
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... they activate complement ... glomerulonephritis, Systemic lupus ... types #allergy #table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... See below for table ... helpful paper complements ... #Differential #Table
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... (e.g. systemic lupus ... erythematosus (SLE
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis ... with systemic lupus ... , WBC casts) especially ... Disease (5%) #Lupus ... Nephritis #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... vasculitis, and SLE
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Epidemiology: -10% of all lupus ... is rare in DIL, SCLE-DIL ... 90% - Low complement ... Discontinuation of causal
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
should use this algorithm ... smallpox, the case ... smallpox-diagnostic-algorithm-poster ... See table below ... all HIGH RISK CASES
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