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differential causes rheumatology alopecia dermatology hairloss sle table diseases druginduced erythematosus focal glomerular glomerulonephritis hematology hemoptysis lad lymphadenopathy management massive
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Algorithm Reactive ... • Systemic Lupus ... #Algorithm #Causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... • Discoid lupus ... #Differential #Diagnosis ... #Algorithm #causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... 90% - Low complement ... 80% - Low complement ... #sle #comparison ... #rheumatology #diagnosis
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
- Differential Diagnosis ... Algorithm Massive ... • Bronchitis Diffuse ... Vasculitis • Lupus ... #Algorithm #Causes
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-retrovirals, Gemcitabine Lupus ... Myopathy • Diffuse ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Differential Diagnosis ... pneumonitis • Diffuse ... enteropathy, and diffuse ... Erythematosus #Diagnosis
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... - Differential Diagnosis ... Algorithm Scarring ... Irreversible-biopsy required • Lupus ... #Algorithm #causes
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
/nephritis • Lupus ... /RPS class IV (diffuse ... nephrology #pathology #comparison ... #table #diagnosis
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