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diagnosis differential pulmonary rheumatology renal syndromes treatment causes classification erythematosus glomerulonephritis hemoptysis hypothermia hypoxemia hypoxia massive mimics progressive protocol prs
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low Complement ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Diagnosis Framework Diffuse ... alveolar hemorrhage + rapidly ... ANCA Associated Vasculitis ... anti-GBM) 10%: - Low Complement ... - Normal Complement
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Differential Diagnosis Algorithm ... • Bronchitis Diffuse ... • Pulmonary Vasculitis ... Malignancy Pulmonary Vasculitis ... • Lupus Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... , proteinuria, rapidly ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... ANCA-associated vasculitis ... pneumonitis • Diffuse ... enteropathy, and diffuse ... RNP antibodies, Complement
Hypoxemia / Hypoxia - Rapid Response Management Algorithm Stridor - Upper airway pathology: • Anaphylaxis • Foreign
Hypoxemia / Hypoxia - Rapid ... Response Management ... Algorithm Stridor ... pathology: • Blood: diffuse ... #Algorithm #rapid
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... hemorrhage (DAH) • Diffuse ... proteinuria • Path: rapidly ... differential #diagnosis #management
Hypothermia - Protocol for ED CORE TEMP < 34º INITIAL THERAPY • Remove wet garments • Avoid rough
(30-34ºC) • Infuse ... large bore IV) • Rapid ... Hypothermia #Protocol #management ... #treatment #algorithm
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