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diagnosis rheumatology classification vasculitis c3 c4 causes cryoglobulinemia cryoglobulins disease erythematosus hematology laboratory lad lymphadenopathy oncology rheumatic rheumatoid sle systemic
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Levels - C3, C4 ... C4 ↓↓ • MCGN type ... C3 ↓ C4 ↓↓ • Cryo ... #Levels #C3 #C4 ... #differential #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... • Systemic Lupus ... • Rheumatoid Arthritis ... #Diagnosis #Algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... rheumatoid factor level ... • Low serum C4 complement ... level • Immunofixation ... (e.g. systemic lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... permanent alopecia Differential ... Kikuchi disease • Type-I ... pneumonitis • Diffuse ... levels (C3 and
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic arthritis ... joint • Systemic lupus ... Tests for All Types ... Screening Tests for Diffuse ... Additional Tests for Diffuse
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... (Low levels mixed
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