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diagnosis rheumatology alopecia causes classification dermatology hairloss vasculitis disease agglutinin anemia arthritis c3 c4 champs cold cryoglobulinemia cryoglobulins erythematosus focal
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Levels - C3, C4 ... C4 ↓↓ • MCGN type ... C3 ↓ C4 ↓↓ • Cryo ... #Levels #C3 #C4 ... #differential #
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Lupus #Nephritis ... #diagnosis #differential ... #types #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
1 (50%-80%), type ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement ... Mnemonic #diagnosis #differential ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... • Systemic Lupus ... #Diagnosis #Algorithm ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... • Discoid lupus ... #Differential # ... Diagnosis #Algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... permanent alopecia Differential ... Kikuchi disease • Type-I ... pneumonitis • Diffuse ... levels (C3 and
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
rheumatoid factor level ... • Low serum C4 complement ... level • Immunofixation ... (e.g. systemic lupus ... classification #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... Tests for All Types ... Screening Tests for Diffuse ... Additional Tests for Diffuse
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Allopecia - Differential ... Disease: Discoid lupus ... Traction alopecia Diffuse ... Scarring Alopecia: Lupus ... • Vitamin D levels
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