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diagnosis hematology agglutinin anemia c4 champs clinicopathology cold erythematosus gammopathy hemolytic hypocomplementemia laboratory levels lupus mgrs mnemonic monoclonal renal rheumatology
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Effect of Selected Diseases ... on Complement Levels ... MCGN type 1 C3 ↓ ... C4 ↓↓ • Cryo ... #differential #
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Cryoglobulinemia (85%), C3 ... Chain deposition disease ... Hypocomplementemia #Low ... #Complement #CHAMPS ... Mnemonic #diagnosis #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
3 Types of Cold ... originate from a low-grade ... hemolysis • C3 ... younger pts) Differential ... temperatures by fixing complement
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Classification: ... permanent alopecia Differential ... • Type-I Interferonopathies
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement ... vasculitis Types ... • No Deposits: C3
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
monkeypox virus or to differentiate ... risk of smallpox –low ... The type of specimen ... depending upon disease ... See table below
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