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differential hematology rheumatology dermatology leukemia management pathophysiology sle syndrome vasculitis chronic classification clinical cns comparison complications druginduced encephalitis hiv infections
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ) CLL Symptoms: ... -> Invade Skin: ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... ’s lymphoma or acute ... #workup #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... Constitutional symptoms ... Discontinuation of causal ... sle #comparison #table ... #rheumatology #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... UV light Incr cell ... inflammation on skin ... pathophysiology #diagnosis ... #signs #symptoms
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... are not caused ... nodes: 13-15%, skin ... (16-32%): lupus ... #Management #Signs
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... #Diagnosis #Clinical
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
sweats (28%) • Skin ... rash (48%) • ... Labs: • CD4+ T-cell ... Treatment: • ART ... Syndrome #HIV #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... that are caused ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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