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differential hematology rheumatology management algorithm classification leukemia sle vasculitis antimda5 antimda5dm chronic clinical common comparison complications dermatomyositis disorders distribution druginduced
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... -> AML: Blast crises ... ) CLL Symptoms: ... -> Invade Skin: ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... #workup #oncology ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... are asthma, allergy ... organ-specific signs ... , skin or esophageal ... #Differential #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... Constitutional symptoms ... NPSLE rare, Malar rash ... sle #comparison #table ... #rheumatology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... UV light Incr cell ... inflammation on skin ... pathophysiology #diagnosis ... #signs #symptoms
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Autoimmune Vasculitis (lupus ... deficiency Work ... cryoglobulins • Skin ... #dermatology #physicalexam
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... CD4+/CD8+ ratio are ... #rheumatology #dermatology ... #diagnosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... are not caused ... nodes: 13-15%, skin ... (16-32%): lupus ... #Management #Signs
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