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differential hematology management dermatology rheumatology algorithm classification sle vasculitis addisons adrenal chronic clinical comparison complications disease druginduced endocrinology eosinophil eosinophilia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... are asthma, allergy ... organ-specific signs ... , skin or esophageal ... #Differential #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... lymphoproliferative disorders ... #workup #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... Constitutional symptoms ... NPSLE rare, Malar rash ... sle #comparison #table ... #rheumatology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... UV light Incr cell ... inflammation on skin ... pathophysiology #diagnosis ... #signs #symptoms
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Vasculitis - Collagen disorders ... Autoimmune Vasculitis (lupus ... deficiency Work ... cryoglobulins • Skin
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... EBV viral load, signs ... to 50% of PTLD cases ... transplantation are ... #oncology #diagnosis
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Infiltrative Disorders ... cancer • Renal cell ... Serum DHEAS Diagnosis ... patches on the skin ... #signs #symptoms
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... #Diagnosis #Clinical
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... are not caused ... nodes: 13-15%, skin ... (16-32%): lupus ... #Management #Signs
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