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diagnosis rheumatology dermatology differential hematology management sle vasculitis chronic classification clinical comparison complications druginduced leukemia lymphocytic manifestations mds mucocutaneous myelodysplasia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... Constitutional symptoms ... NPSLE rare, Malar rash ... Discontinuation of causal ... sle #comparison #table
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... UV light Incr cell ... inflammation on skin ... pathophysiology #diagnosis #signs ... #symptoms #complications
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... Leukemia #diagnosis #workup ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... faint that they are
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
are not caused ... Self-limiting, chronic but stable ... nodes: 13-15%, skin ... (16-32%): lupus ... Diagnosis #Management #Signs
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... just beneath the skin ... that are caused ... diagnosis #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... loss, arthralgia, arm ... bruits, asymmetric arm ... , mucositis • Rash ... tract, and often causes
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