11 results
diagnosis hematology differential leukemia chronic lymphocytic management agglutinin causes cellulitis classification clinical cold hemeonc hodgkins legs lymphoma mds monoclonal myelodysplasia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... inclusions - If infection ... bartonella (oroya fever ... #workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... DAT (-) → Sickle Cell ... malignancy, autoimmune disease ... Recent travel/Fevers ... , DAT (-) → Infection
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Symptoms: High fevers ... #hemolytic #anemia ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... - infiltrates (anemia ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac disease
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... cells can indicate disease ... • Neutropenia, anemia ... #oncology #hematology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
All oysters at Chesapeake ... Rapid onset of fever ... hemochromatosis, hemolytic ... anemia, CKD, hiv ... rash #cellulitis #dermatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... ) B symptoms → fevers ... Complications: 1) Infection ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... • Coombs (-) hemolytic ... anemia due to cold ... Differential #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... • Parvovirus infection ... Workup: • Complete ... #oncology
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